Rare Psychiatry News
Advertisement
Disease Profile
Cholera
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
<1 >
Age of onset
All ages
ICD-10
A00.0 A00.1 A00.9
Inheritance
Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.
Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.
X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
Not applicable
Other names (AKA)
Vibrio cholerae infection
Categories
Bacterial infections
Summary
Cholera is an infection of the small intestines that is caused by the bacterium Vibrio cholera. The condition can range from mild to severe and many affected people may have no obvious signs or symptoms. Approximately 5-10% of infected people will have severe disease with watery diarrhea and vomiting leading to rapid fluid loss, dehydration, and shock. If left untreated, this can cause acute renal failure, severe electrolyte imbalances, coma, or even death. People develop cholera when they eat food or drink water that is contaminated with Vibrio cholera. The condition occurs most often in places that lack water treatment and have poor sanitation and inadequate hygiene. Treatment aims to prevent dehydration and replace the fluids and salts that are lost through diarrhea.[1][2][3]
Symptoms
This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
Medical Terms | Other Names |
Learn More:
HPO ID
|
---|---|---|
80%-99% of people have these symptoms | ||
Diarrhea |
Watery stool
|
0002014 |
30%-79% of people have these symptoms | ||
Decreased urine output | 0011037 | |
Dehydration | 0001944 | |
Hypocalcemia |
Low blood calcium levels
|
0002901 |
Hypokalemia |
Low blood potassium levels
|
0002900 |
Hyponatremia |
Low blood sodium levels
|
0002902 |
Hypotension |
Low blood pressure
|
0002615 |
Muscle spasm | 0003394 | |
Muscle weakness |
Muscular weakness
|
0001324 |
Tachycardia |
Fast heart rate
Heart racing
Racing heart
[ more ] |
0001649 |
Vomiting |
Throwing up
|
0002013 |
5%-29% of people have these symptoms | ||
Abdominal cramps | 0032155 | |
Achlorhydria | 0032448 | |
Acute kidney injury | 0001919 | |
Deeply set eye |
Deep set eye
Deep-set eyes
Sunken eye
[ more ] |
0000490 |
Hyperventilation |
Rapid breathing
|
0002883 |
Low blood sugar
|
0001943 | |
Hypovolemic shock | 0031274 | |
Irritability |
Irritable
|
0000737 |
Lactic acidosis |
Increased lactate in body
|
0003128 |
Lethargy | 0001254 | |
Loss of consciousness |
Passing out
|
0007185 |
Palmoplantar cutis laxa |
Excessive wrinkled skin of palms and soles
Increased wrinkles of palms and soles
Wrinkled palms and soles
Wrinkled skin of hands and feet
[ more ] |
0007517 |
Premature birth |
Premature delivery of affected infants
Preterm delivery
[ more ] |
0001622 |
0001250 | ||
Spontaneous abortion | 0005268 | |
Tachypnea |
Increased respiratory rate or depth of breathing
|
0002789 |
1%-4% of people have these symptoms | ||
Aspiration pneumonia | 0011951 | |
Fever | 0001945 | |
Stroke | 0001297 |
Related diseases
Related diseases are conditions that have similar signs and symptoms. A health care provider may consider these conditions in the table below when making a diagnosis. Please note that the table may not include all the possible conditions related to this disease.
Conditions with similar signs and symptoms from Orphanet
|
---|
Mild cases can be confused with other causes of gastroenteritis such as Escherichia coli and rotavirus infections.
Visit the Orphanet disease page for more information.
|
Learn more
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- You can obtain information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.
- Mayo Clinic has an information page on Cholera.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
In-Depth Information
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Cholera. Click on the link to view a sample search on this topic.
References
- Sajeev Handa, MBBCh, BAO, LRCSI, LRCPI. Cholera. Medscape Reference. February 2016; https://emedicine.medscape.com/article/962643-overview.
- Cholera. MedlinePlus. May 2014; https://www.nlm.nih.gov/medlineplus/ency/article/000303.htm.
- Cholera Vibrio cholerae infection. Centers for Disease Control and Prevention. October 2014; https://www.cdc.gov/cholera/index.html.